Tag Archives: perineural invasion

Perineural Invasion

Posted on August 21, 2012 by admin2

Perineural invasion (PI) in skin cancers is a significant finding potentially requiring additional treatment. There are four levels of PI: perineural inflammation, minimal microscopic invasion of small nerves, larger nerve invasion, and invasion with clinical symptoms (pain, numbness, or motor … Continue reading →

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Squamous Cell Carcinoma of lower lip – Subtotal Involvement

Posted on May 11, 2011 by admin2

Thirty something year old with total lower lip reconstruction following excision of Squamous Cell carcinoma (SCCa) lower lip Mohs. Continue reading →

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Perineural Invasion

Posted on March 18, 2011 by admin2

Perineural invasion is strongly indicative of aggressive behavior and risk of metastases. True perineural invasion requires histologic finding of cancer invasion of the nerve or cancer invasion of  the epineurium adjacent to the nerve.  This must be distinguished from cancer … Continue reading →

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Squamous Cell Carcinoma Lower Lip

Posted on March 18, 2011 by admin2

A man in his thirties with lifelong h/o severe actinic cheilitis of left lower lip. Biopsy found squamous cell carcinoma with perineural invasion. Continue reading →

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