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Tag Archives: Actinic Keratoses
Actinic keratosis (AK) is the most common sun-damage related precancerous lesion of the skin. The mainstay of treatment of these scaly rough lesions had been liquid nitrogen cryotherapy. Recently, several new treatments have been proven to be effective including Zyclara … Continue reading
Posted in Clinical Pearls
Tagged actinic cheilitis, Actinic Keratoses, actinic keratosis
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This is a sixty something year old on Prograf and Cellcept with multiple squamous cell carcinomas (SCCa) and actinic keratoses (AK). He has used Carac, Solaraze, and Aldara with limited results.
Recommendations included consideration of changing the patient from tacrolimus (Prograf) to sirolimus (Rapamune) Rapamune had been shown to have no effect on keratinocytes and thus not promote SCCa growth. Continue reading